Table 3 Adverse drug event outcomes in OMOP mapped to MeSH terms at different abstraction levels
Aggregation | ORIGINAL | LOW (IC 7–10) | MEDIUM (IC 4.5–7) | HIGH (IC 1–5.5) | MeSH 2nd level |
|---|---|---|---|---|---|
Acute kidney injury | Acute kidney injury, Kidney tubular necrosis, acute | Acute kidney injury D058186 (5th level) IC: 9.34 | Kidney Diseases D007674 (3rd level) IC: 5.73 | Urologic Diseases D014570 (2nd level) IC: 5.16 | Urologic Diseases D014570 (2nd level) IC: 5.16 |
Acute Liver injury | Drug-induced liver injury, Drug-induced liver injury, chronic | Drug-Induced Liver Injury D056486 (3rd level) IC: 9.87 | Liver Diseases D008107 (2nd level) IC: 5.64 | Digestive System Diseases D004066 (1st level) IC: 4.01 | Liver Diseases D008107 (2nd level) IC: 5.64 |
Acute Myocardial Infarction | Myocardial infarction, Anterior wall MI, Inferior wall MI, Myocardial stunning, Shock, cardiogenic | Myocardial infarction D009203 (4th level) IC: 7.22 | Myocardial Ischemia D017202 (3rd level) IC: 5.94 | Heart Diseases D006331 (2nd level) IC: 4.61 | Heart Diseases D006331 (2nd level) IC: 4.61 |
GI bleed | GI Hemorrhage, Hematemesis, Melena, Peptic ulcer hemorrhage | Gastrointestinal Hemorrhage D006471 (3rd level) IC: 9.00 | Gastrointestinal Diseases D005767 (2nd level) IC: 4.87 | Digestive System Diseases D004066 (1st level) IC: 4.01 | Gastrointestinal Diseases D005767 (2nd level) IC: 4.87 |