Table 4 Running time (seconds) for warm-start versus cold-started gene essentiality analysis in quad-precision using Quad MINOS (one LP is run for each reaction at a single growth rate)
From: solveME: fast and reliable solution of nonlinear ME models
Model | Genes | Warm-start | Cold-start | Speed-up |
|---|---|---|---|---|
E. coli ME (reduced) | 1424 | 3130.8 | 58967.4 | 19× |
T. maritima ME [3] | 613a | 5.26 h | >60 h | 12× |