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Table 1 Comparison of GeneSCF features with other functional enrichment tools

From: GeneSCF: a real-time based functional enrichment tool with support for multiple organisms

 

Input type

Database update

Functional Database support

Multiple organism support

Limitations for input genes

Statistics

GeneSCF v1.1

List of genes

Real-time

KEGG, GO, Reactome and NCG

Yes

No upper or lower limit

FE test a & FDR b

GeneSCF v1.0

List of genes

Manual (preparation needed)

KEGG, GO, Reactome and NCG

No (Homo sapiens)

No upper or lower limit

FE test & FDR

GOrilla

List of genes

Weekly auto-update

GO

Yes

No upper limit but has lower limit

FE test & FDR

DAVID 6.7

List of genes

Last known update 2010)

KEGG, GO, Reactome and Biocarta

Yes

Upper limit 3000 and no lower limit

FE test & FDR

  1. aFisher’s Exact test
  2. bFalse Discovery Rate based methods for multiple testing correction