Table 2 The top ten Gene Ontology terms enriched. GO annotation analysis was performed on the shared members derived from the drug-signaling pathways of fluphenazine and estradiol
From: Drug voyager: a computational platform for exploring unintended drug action
GO term | Description | P-value | FDR q-value |
|---|---|---|---|
GO:1904029 | regulation of cyclin-dependent protein kinase activity | 1.11E-09 | 9.24E-06 |
GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 1.11E-09 | 4.62E-06 |
GO:0051726 | regulation of cell cycle | 1.28E-09 | 3.54E-06 |
GO:0051301 | cell division | 1.37E-09 | 2.83E-06 |
GO:0051290 | protein heterotetramerization | 4.61E-09 | 7.64E-06 |
GO:0034723 | DNA replication-dependent nucleosome organization | 1.55E-08 | 2.14E-05 |
GO:0006335 | DNA replication-dependent nucleosome assembly | 1.55E-08 | 1.83E-05 |
GO:0006334 | nucleosome assembly | 1.58E-08 | 1.63E-05 |
GO:0051262 | protein tetramerization | 4.87E-08 | 4.48E-05 |
GO:0007186 | G-protein coupled receptor signaling pathway | 5.95E-08 | 4.94E-05 |