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Table 7 Hub genes from the estimated graphs using the SPACE and ESPACE methods

From: Enhanced construction of gene regulatory networks using hub gene information

SPACE

ESPACE

No.

Gene

Degree

No.

Gene

Degree

1

PRC1

26

1

AURKA

36

2

RRM2

17

2

NKX2-1

35

3

GPR116

16

3

RRM2

18

4

NKX2-1

16

4

CYP2B7P1

16

5

CYP2B7P1

15

5

GPR116

16

6

SFTPB

15

6

SFTPB

15

7

HOP

13

7

HOP

12

8

C1orf116

12

8

HSD17B6

11

9

HSD17B6

12

9

PRC1

11

10

TFF1

12

10

TFF1

11

11

CD302

10

11

C1orf116

10

12

FMO5

10

12

CD302

10

13

TPX2

8

13

FMO5

10

   

14

UBE2C

10

   

15

APC

8

   

16

CDKN3

8

   

17

TPX2

8

  1. Bold font denotes the genes only identified by the modified method