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Table 3 Assembled results of in silico generated data sets from the reference HBV genome by different methodsa

From: De novo assembly of highly polymorphic metagenomic data using in situ generated reference sequences and a novel BLAST-based assembly pipeline

Data set size

Method

BBAP FD

Velvet

SOAPdenovo

Genovo

Error rate

10−4

10−3

10−2

10−4

10−3

10−2

10−4

10−3

10−2

10−4

10−3

10−2

55X

Coverage

1

1

1

1

1

1

0

0

1

1

1

1

Accuracy

1

1

0.99

1

1

1

0

0

1

1

1

1

# of contigs

1

1

2

1

1

1

0

0

1

1

1

1

557X

Coverage

1

1

1

1

0.99

1

0

1

0.27

1

1

1

Accuracy

1

1

1

1

1

0.99

0

0.99

0.99

1

1

1

# of contigs

1

1

2

1

1

9

0

1

5

1

1

1

5,579X

Coverage

1

1

1

0.99

0.96

0.03

1

0.01

0.43

1

1

1

Accuracy

1

1

1

1

1

0.59

1

0.20

0.99

1

1

0.99

# of contigs

1

1

1

1

6

1

1

0

11

1

1

1

55,799X

Coverage

1

1

1

0.98

0

0.11

0.02

0

0.04

1

1

1

Accuracy

1

1

1

1

0

0.97

0.40

0

0.80

1

1

0.99

# of contigs

1

1

1

3

0

2

0

0

1

3

2

5

  1. aResults represent averages of the assembly results of 5 replicate data sets. Bold areas indicate average assembly results with <80% coverage