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Fig. 9 | BMC Bioinformatics

Fig. 9

From: Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks

Fig. 9

Structure-based prediction of PPIs for the human immune disease pathway. a Network diagram of the human immune disease pathway. Yellow circles (nodes) represent individual proteins connected by interactions (edges). Three types of interactions are denoted by edges in different colors, positive predictions are blue, true positives (predicted interactions also present in the Reactome database) are green, and false negatives (interactions from Reactome that are not predicted) are red. b Matrix of binary interactions including positive predictions (blue), true positives (green), and false negatives (red). Circles marked with a star and a dot show those protein pair that pass and fail the CC filter, respectively. UniProt IDs of proteins involved in this pathway according to the Reactome database are shown in both a and b

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BMC Bioinformatics

ISSN: 1471-2105

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