Skip to main content

Table 1 Comparison of the success rates for protein dimers assembled from the crystal structures and computer-generated models of monomers

From: Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks

Protocol

Crystal structures

Protein models

iRMSD ≤2.5 Å

PCS ≥0.65

iRMSD ≤8.5 Å

PCS ≥0.30

ZDOCK

51.5%

52.1%

28.1%

23.2%

ZDOCK + eRankPPI

58.3%

59.6%

43.7%

39.3%

ZDOCK + eRankPPI + FiberDock

72.8%

73.2%

52.4%

48.7%

  1. The acceptance criteria for correct predictions are an iRMSD of ≤2.5 Å and PCS ≥0.65 for crystal structures, and an iRMSD of ≤8.5 Å and PCS ≥0.30 for protein models. The best of top 10 dimer models is considered
Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us