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Table 1 Influences of reverse ecology-based measures on pathogen/non-pathogen classification

From: Limitations of a metabolic network-based reverse ecology method for inferring host–pathogen interactions

Variables

Mammalian pathogens

Plant pathogens

Insect pathogens

Estimate[Averaged]

Estimate[Best]

Estimate[Averaged]

Estimate[Best]

Estimate[Averaged]

Estimate[Best]

BSSHM

1.505 (<0.01)

1.485 (<0.01)

2.058 (0.03)

2.347 (0.01)

2.356 (0.01)

2.592 (<0.01)

BSSMH

0.086 (0.74)

 

0.51 (0.55)

 

−1.787 (0.03)

−1.871 (0.02)

MCIHM

−1.191 (<0.01)

−1.201 (<0.01)

−2.098 (0.06)

−2.124 (0.05)

−2.135 (0.02)

−2.265 (0.01)

MCIMH

0.083 (0.75)

 

2.043 (<0.01)

2.134 (<0.01)

2.365 (0.01)

2.727 (<0.01)

AICc

 

284.4

 

87.6

 

111.2

  1. BSSHM and BSSMH correspond to the biosynthetic support score (BSS) of hosts for microbes and the BSS of microbes for hosts, respectively. MCIHM and MCIMH are the metabolic complement index (MCI) of hosts for microbes and the MCI of microbes for hosts, respectively. Estimates in the best and averaged models based on logistic regression are shown. Values in brackets indicate associated p-values. Values in bold indicate statistical significance. AICc denotes the sample size-corrected version of the Akaike information criterion value