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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Improved quality metrics for association and reproducibility in chromatin accessibility data using mutual information

Fig. 3

Synthetic replicate bivariate plots and statistical profiles. A Scatter plots displaying counts per genomic bin (10 kb in size) of whole fragments per kilobase per million (WFpkm) between two synthetic replicates (x- and y-axis) generated in process Fig. 2A–C. The percentage of shared peaks decreases between the two simulated replicates from top to bottom. B Correlation values (y-axis) as a function of percentage of shared peaks between synthetic replicates (x-axis). C Association scores (y-axis) as a function of the percent of shared peaks between synthetic replicates (x-axis). In B and C, red and grey curves depict the mean and 95% confidence interval (respectively) across simulations. A dashed line marks a one-to-one relationship between the x- and y-axis. Left and right columns display change in values as a function of removing co-zeros

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