Fig. 1

Recognition of CD34⁺CD38⁻ LSC clones using differentiation trajectory and changes in signal molecules in time-series before and after cytokine induction. a Differentiation trajectory inference in SJ03; b primitive cells emphasized in red with CD34⁺CD38⁻ phenotype, cells with 0.1 < psudotime < 0.8 is labelled by green; c time-series heatmap of the reported penal in which mature blasts express CD11b⁺CD45^high (blue arrow); d, e pSTAT3 and pSTAT5 expression increases in the early stage of G-CSF induction; f, g Akt showed a slight response to the effect of Flt3L and SCF; h Increased expression of pSTAT3 after IL-10 induction was observed in the intermediate and late stages