A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics

Table 5 Statistical measures of different values of \(\lambda\) for RWEP

Datasets	Measures	0.1	0.2	0.3	0.4	0.5	0.6	0.7	0.8	0.9	1
DIP	SN	0.5004	0.5347	0.5338	0.5296	0.5201	0.5167	0.5047	0.5021	0.4996	0.5004
	SP	0.8245	0.8347	0.8344	0.8332	0.8304	0.8293	0.8258	0.8250	0.8242	0.8245
	PPV	0.4588	0.4902	0.4894	0.4855	0.4768	0.4737	0.4627	0.4603	0.4580	0.4588
	NPV	0.8474	0.8579	0.8576	0.8563	0.8534	0.8524	0.8487	0.8479	0.8471	0.8474
	F	0.4951	0.5115	0.5107	0.5066	0.4975	0.4943	0.4828	0.4803	0.4779	0.4786
	ACC	0.7581	0.7660	0.7656	0.7636	0.7593	0.7577	0.7522	0.7510	0.7499	0.7502
BioGRID	SN	0.5675	0.5667	0.5550	0.5475	0.5392	0.5308	0.5233	0.5200	0.5150	0.5133
	SP	0.8359	0.8356	0.8324	0.8304	0.8282	0.8259	0.8239	0.8230	0.8216	0.8212
	PPV	0.4830	0.4823	0.4723	0.4660	0.4589	0.4518	0.4454	0.4426	0.4383	0.4369
	NPV	0.8774	0.8771	0.8738	0.8716	0.8693	0.8669	0.8648	0.8638	0.8624	0.8619
	F	0.5218	0.5211	0.5103	0.5034	0.4958	0.4881	0.4812	0.4782	0.4736	0.4720
	ACC	0.7788	0.7784	0.7734	0.7702	0.7667	0.7631	0.7599	0.7585	0.7564	0.7557
Fruitfly	SN	0.2535	0.2556	0.2637	0.2657	0.2657	0.2677	0.2677	0.2677	0.2698	0.2535
	SP	0.9104	0.9106	0.9111	0.9112	0.9112	0.9114	0.9114	0.9114	0.9115	0.9104
	PPV	0.1607	0.1620	0.1671	0.1684	0.1684	0.1697	0.1697	0.1697	0.1710	0.1607
	NPV	0.9475	0.9476	0.9482	0.9483	0.9483	0.9485	0.9485	0.9485	0.9486	0.9475
	F	0.1967	0.1983	0.2046	0.2061	0.2061	0.2077	0.2077	0.2077	0.2093	0.1967
	ACC	0.8688	0.8691	0.8701	0.8704	0.8704	0.8706	0.8706	0.8706	0.8709	0.8688

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