Table 4 Virus-wise comparison between SCADDx and LOADDx using CTD KB
Dataset | Algorithm (Parameters) | Virus | Subjects (\(S^{+}/S\)) | Accuracy n@1 (%) | Accuracy n@2 (%) | Accuracy n@3 (%) | Accuracy n@4 (%) | Accuracy n@5 (%) | Accuracy n@10 (%) |
|---|---|---|---|---|---|---|---|---|---|
Dataset 1 Testset 1a (GSE73072) | SCADDx P = 100 Q = 175 | H1N1 virus | 1/2 | 50 | 50 | 50 | 50 | 50 | 50 |
H3N2 virus | 1/3 | 100 | 100 | 100 | 100 | 100 | 100 | ||
HRV virus | 4/5 | 100 | 100 | 100 | 100 | 100 | 100 | ||
RSV virus | 2/3 | 33.33 | 33.33 | 33.33 | 33.33 | 33.33 | 66.66 | ||
LOADDx P = 25 Q = 225 | H1N1 virus | 1/2 | 50 | 50 | 50 | 50 | 50 | 50 | |
H3N2 virus | 1/3 | 100 | 100 | 100 | 100 | 100 | 100 | ||
HRV virus | 4/5 | 80 | 80 | 80 | 80 | 80 | 80 | ||
RSV virus | 2/3 | 33.33 | 33.33 | 33.33 | 33.33 | 33.33 | 33.33 | ||
Dataset 1 Testset 1b (GSE73072) | SCADDx P = 100 Q = 175 | H1N1 virus | 2/3 | 100 | 100 | 100 | 100 | 100 | 100 |
H3N2 virus | 3/4 | 75 | 75 | 75 | 75 | 75 | 75 | ||
HRV virus | 2/3 | 100 | 100 | 100 | 100 | 100 | 100 | ||
RSV virus | 1/3 | 66.66 | 33.33 | 33.33 | 33.33 | 33.33 | 33.33 | ||
LOADDx P = 25 Q = 225 | H1N1 virus | 2/3 | 100 | 100 | 100 | 100 | 100 | 100 | |
H3N2 virus | 3/4 | 75 | 75 | 75 | 75 | 75 | 75 | ||
HRV virus | 2/3 | 100 | 100 | 100 | 100 | 100 | 100 | ||
RSV virus | 1/3 | 66.66 | 66.66 | 66.66 | 66.66 | 66.66 | 66.66 | ||
Dataset 2 Testset 2a (GSE68310) | SCADDx P = 150 Q = 300 | Influenza A virus | 7/7 | 100 | 100 | 100 | 100 | 100 | 100 |
Other viruses | 3/3 | 100 | 100 | 100 | 100 | 100 | 100 | ||
HRV virus | 5/5 | 100 | 100 | 100 | 100 | 100 | 100 | ||
Infected but no virus subtype detected | 1/1 | 100 | 100 | 100 | 100 | 100 | 100 | ||
LOADDx P = 50 Q = 300 | Influenza A virus | 7/7 | 85.71 | 85.71 | 100 | 100 | 100 | 100 | |
Other viruses | 3/3 | 66.66 | 66.66 | 66.66 | 66.66 | 100 | 100 | ||
HRV virus | 5/5 | 80 | 100 | 100 | 100 | 100 | 100 | ||
Infected but no virus subtype detected | 1/1 | 0 | 0 | 0 | 0 | 0 | 100 | ||
Dataset 2 Testset 2b (GSE68310) | SCADDx P = 150 Q = 300 | Influenza A virus | 5/5 | 100 | 100 | 100 | 100 | 100 | 100 |
Other viruses | 5/5 | 100 | 100 | 100 | 100 | 100 | 100 | ||
HRV virus | 1/1 | 0 | 0 | 0 | 0 | 0 | 100 | ||
Infected but no virus subtype detected | 4/4 | 75 | 100 | 100 | 100 | 100 | 100 | ||
LOADDx P = 50 Q = 300 | Influenza A virus | 5/5 | 80 | 80 | 80 | 80 | 80 | 100 | |
Other viruses | 5/5 | 100 | 100 | 100 | 100 | 100 | 100 | ||
HRV virus | 1/1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
Infected but no virus subtype detected | 4/4 | 75 | 75 | 75 | 75 | 75 | 75 | ||
Dataset 3 (GSE90732) | SCADDx P = 25 Q = 25 | H1N1 virus | 4/4 | 100 | 100 | 100 | 100 | 100 | 100 |
LOADDx P = 25 Q = 25 | H1N1 virus | 4/4 | 75 | 100 | 100 | 100 | 100 | 100 | |
Dataset 4 (GSE61754) | SCADDx P = 25 Q = 25 | H3N2 virus | 4/7 | 85.71 | 85.71 | 85.71 | 85.71 | 85.71 | 85.71 |
LOADDx P = 25 Q = 50 | H3N2 virus | 4/7 | 85.71 | 85.71 | 85.71 | 85.71 | 85.71 | 85.71 |