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Table 1 2018 EANBiT-RT program

From: Designing and delivering bioinformatics project-based learning in East Africa

Date

Course

11–15 June 2018 (Week 01)

*Introduction lectures on bioinformatics

*Introduction lectures on molecular biology

*Introduction Lectures on Computing for Biology

*Presentation of the recent history (since Sanger Sequencing) of sequencing technologies

18 July–06 July 2018 (Week 02–04)

*Basic experimental design, biostatistics, manipulation of tabular data in R, and basic visualization (Scatter plots, box plots, regression lines)

*Sequence alignments, BLAST tools, motifs, homology modeling (HMMs), profile databases (Pfam, Prosite, etc.)

*Introduction to NGS data (Illumina short reads technology), their vocabulary (coverage, clusters, reads, etc.), and their different uses: RNAseq, whole genome assembly, amplicon sequencing

*Whole genome assembly (de novo and reference-based)

*Genome annotation

* Barcodes, markers, and 16S rRNA analysis, Metagenomics/Microbiomes

*Molecular evolution and phylogenetics, selection pressure (dN/dS analyses)

*Population structure, Population genetics

*Polymorphisms, variant calls, and genome-wide analysis studies (GWAS)

*Genomic selection, marker-assisted selection

*Transcriptomics

*Protein structure, folding

*Advanced UNIX command line (Bash scripting, sed, awk, etc.)

*Advanced Python

*Detailed analysis of Oxford Nanopore data sets

09–13 July 2018 (Week 05)

*Scientific writing (papers and proposals)

Scientific communication (to an audience of non-specialists)

*Grant writing

*Project management (Gantt charts, monitoring, evaluation, etc.)

*Pedagogy

*Academic integrity, authorship, collaboration management (MoU), supervision, leadership skills, and conflict resolution

* Research ethics (responsible conduct, research on human subjects, etc.)

*Literature management (references, online journal databases) and paper critique

*Open Science, Issues of Reproducibility, Open Source Data, and Publications