Fig. 4

A network whose edge weights are the difference of those for the networks of Healthy and Stage_0, and the values are expressed as the thickness and density of the edges (the weight is 0 when there is no edge). The size (area) of the node represents the QNetDiff score. Nodes are arranged in counterclockwise order of QNetDiff score, and Actinomyces is the bacteria with the largest QNetDiff score. Granulicatella has been reported to form a biofilm in the oral cavity together with Fusobacterium, which is known to increase with the progression of colorectal cancer