Fig. 1
From: Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness
A brief overview of chromatin loops. The green-colored ring-shaped protein first pulls DNA through it creating a loop. CTCF as a binder or lock for this ring and widely known as CCCTC binding or transcription factor. TADs [11] are formed by the folding of chromatin, which is a complex of DNA, RNA, and proteins. The ring-shaped protein, which tightens the loops is called the cohesin [65]