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Table 2 Consistency score using CTCF, H3K27ac and RNAPII recovery between high and low resolution

From: Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness

Tools

CTCF (%)

H3K27ac (%)

RNAPII (%)

Consistency score (%)

Chromosight

0.00

0.00

0.00

0.00

cLoops***

100.00

100.00

100.00

100.00

cLoops2***

99.70

95.35

98.20

97.75

FitHiC2

97.74

98.84

99.41

98.66

FitHiChIP

72.33

97.57

97.15

89.02

HiCCUPS*

81.07

85.19

91.95

86.07

HiCExplorer**

88.37

90.91

97.48

92.25

LASCA

90.06

94.55

94.63

93.08

Mustache

88.24

89.69

97.80

91.91

Peakachu

63.93

94.88

93.37

84.06

SIP

73.86

73.15

93.00

80.00

  1. HiCCUPS* and HiCExplorer** didn’t produce results at low resolutions and cLoops*** and cLoops2*** do not have a resolution parameter