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Table 3 Biological score averaging CTCF, H3K27ac and RNAPII recovery efficiency rate

From: Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness

Tools

CTCF (%)

H3K27ac (%)

RNAPII (%)

Biological score (%)

Chromosight

66.0440723

80.81

54.12

66.99

cLoops***

100

100.00

100.00

100.00

cLoops2***

8.311488926

1.88

0.00

3.40

FitHiC2

0

0.00

0.70

0.23

FitHiChIP

28.26098576

17.81

19.30

21.79

HiCCUPS*

18.46754736

16.26

7.33

14.02

HiCExplorer**

10.76000424

9.68

1.62

7.35

LASCA

4.244814356

3.00

2.48

3.24

Mustache

4.687381023

5.15

0.15

3.33

Peakachu

28.60921051

6.65

5.26

13.51

SIP

21.96560705

14.75

2.88

13.20

  1. HiCCUPS* and HiCExplorer** didn’t produce results at low resolutions and cLoops*** and cLoops2*** do not have a resolution parameter