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Table 1 5-Fold cross-validation performances of methods on Martin dataset

From: xCAPT5: protein–protein interaction prediction using deep and wide multi-kernel pooling convolutional neural networks with protein language model

Method

Accuracy (%)

Precision (%)

Recall (%)

Specificity (%)

F1-Score (%)

MCC (%)

PIPR (2019)

80.84 ± 0.44

81.44 ± 0.69

81.55 ± 0.85

80.32 ± 0.67

81.43 ± 0.45

61.69 ± 0.89

FSNN-LGBM (2021)

96.49 ± 0.13

96.03 ± 0.26

97.23 ± 0.04

95.69 ± 0.29

96.62 ± 0.12

92.98 ± 0.25

GcForestPPI (2021)

89.26

88.95

89.71

NA

88.33

78.57

MARPPI (2023)

91.80 ± 1.16

90.69 ± 2.68

94.51 ± 1.13

91.22 ± 1.25

NA

83.74 ± 2.32

HNSPPI (2023)

93.21 ± 0.35

88.47 ± 0.53

99.39 ± 0.21

NA

93.59 ± 0.32

93.21 ± 0.35

EresCNN (2023)

87.89

87.84

87.96

NA

87.90

75.81

Our xCAPT5

97.27 ± 0.12

97.30 ± 0.24

97.07 ± 0.20

97.44 ± 0.11

97.18 ± 0.25

94.82 ± 0.20

  1. NA denotes that data is not available. Report with mean and standard deviation. The bold is the best performance in each metric