Fig. 13

Prediction and uncertainty heatmaps on an example slide in the external test set. Heatmaps of HPV predictions and uncertainty were generated from the final tile-based model for a randomly selected slide from the test set. Two areas are shown with magnified display. Area 1 is a location with intermediate predictions and high uncertainty, showing mostly stroma and out-of-focus cells in the top-right corner. Area 2 is a location with strong HPV-negative predictions and low uncertainty, showing heavy keratinization and pleomorphic nuclei