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Table 1 Scores of algorithms when aligning short reads to REF-1

From: Mora: abundance aware metagenomic read re-assignment for disentangling similar strains

Algorithm

Strain

Species

Genus

F1

Sensitivity

Precision

F1

Sensitivity

Precision

F1

Sensitivity

Precision

Pufferfish

62.12

47.27

90.58

66.04

50.25

96.29

67.92

51.68

99.05

Mora + Pufferfish

66.20

50.37

96.53

67.04

51.01

97.75

68.49

52.11

99.87

AugPatho2 + Pufferfish

66.62

50.69

97.14

66.90

50.90

97.55

68.49

52.11

99.87

Bowtie2

84.54

78.04

92.20

88.94

82.11

97.01

91.21

84.21

99.48

Mora + Bowtie2

87.59

80.86

95.54

89.22

82.37

97.32

91.48

84.46

99.79

AugPatho2 + Bowtie2

89.03

82.19

97.10

89.64

82.76

97.77

91.50

84.47

99.80

Kraken2

NA

NA

NA

88.19

83.57

93.36

92.36

87.52

97.77

Clark

59.38

55.21

64.23

91.12

84.71

98.57

92.04

85.58

99.57

  1. Both Mora and AugPatho2 were able to improve the scores of the initial aligner, though AugPatho2 appears to have a slight systematic edge