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Table 5 Scores between Minimap2, Mora, AugPatho2, Kraken2, and Clark when aligning long simulated reads to REF-2

From: Mora: abundance aware metagenomic read re-assignment for disentangling similar strains

Algorithm

Species

Genus

F1

Sensitivity

Precision

F1

Sensitivity

Precision

Minimap2

65.65

60.32

72.01

83.74

76.95

91.86

Mora

68.86

63.26

75.55

83.96

77.13

92.11

AugPatho2

67.93

63.05

73.62

84.21

78.16

91.27

Kraken2

73.10

68.65

78.16

85.19

80.01

91.09

Clark*

22.97

14.83

50.98

36.10

23.30

80.12

  1. Both Mora and AugPatho2 increase the scores of Minimap2. Mora slightly outperforms AugPatho2 at the species level but has slightly lower F1 and sensitivity scores at the genus level. Clark has an asterisk to signify that had an issue with building the database, which resulted in the low scores