Open Access

Erratum to: Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity

BMC Bioinformatics201011:463

DOI: 10.1186/1471-2105-11-463

Received: 15 September 2010

Accepted: 16 September 2010

Published: 16 September 2010

The original article was published in BMC Bioinformatics 2005 6:182


In the original manuscript [1], Equations (1) and (4) were erroneous and are given below in their correct form:
M a = 2 c O c ln O c E c = 2 c O c ln f c g c
The text referring to equation (1) states the value should be computed as the G-test statistic, which equals to 2*sum(O*ln(O/E)); therefore, the accompanying text is correct.
C = a ( r a 1 ) L 0.5

The text "a constant of 0.5 is added to the correction factor C" in the paragraph following equation (4), should state: "a constant of 0.5 is subtracted from the correction factor C".

The error in the formulae does not affect the results in the paper regarding performance of MILC, MELP and other codon distance measures as all calculations were performed using a correct implementation of MILC in the INCA software [2].


Authors’ Affiliations

Division of Electronics, Rudjer Boskovic Institute
Division of Biology, Faculty of Science, University of Zagreb
Department of Informatics, University of Oslo


  1. Supek F, Vlahovicek K: Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity. BMC Bioinformatics 2005, 6: 182. 10.1186/1471-2105-6-182View ArticlePubMedPubMed CentralGoogle Scholar
  2. Supek F, Vlahovicek K: INCA: synonymous codon usage analysis and clustering by means of self-organizing map. Bioinformatics 2004, 20(14):2329–2330. 10.1093/bioinformatics/bth238View ArticlePubMedGoogle Scholar


© Supek and Vlahoviček; licensee BioMed Central Ltd. 2010

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