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Table 5 MDSS-based bridges for JIA domain

From: Exploring and linking biomedical resources through multidimensional semantic spaces

Disease

ProteinGene

Score

S

anemias

erythropoietin

coh = 0.500

2

psoriasis

TNF human

coh = 0.333

2

psoriasis

fusion protein

conf = 0.333

3

periodic syndrome

TNF receptors

coh = 1.000

2

systemic onset JIA

receptors IL-6

coh = 0.114

8

rickets celiac

gluten

coh = 0.500

2

tuberculous infections

TNF blockers infliximab

conf = 0.222

2

ACLS (*)

lupus coagulation inhibitor

f1 = 0.500

2

third disease

vaccine rubella

conf = 1.000

3

diseases autoimmune

tyrosine phosphatases protein

coh = 0.500

2

syndrome laron

insulinlike growth factor

conf = 1.000

2

disorder amyloid

substance amyloid

f1 = 0.141

5

osteoarthrosis oa

proteoglycans

f1 = 0.188

3

growth failure

insulinlike growth factor

conf = 0.667

2

thyromegaly

substance amyloid

conf = 0.600

3

syndrome macrophage activation

perforin

coh = 0.571

4

syndrome macrophage activation

cyclosporine medication

f1 = 0.311

14

uveitis

factors antinuclear

conf = 0.171

19

systemic JIA

IL-1 receptor antagonist protein

conf = 0.133

2

syndrome hemophagocytic

perforin

coh = 0.286

2

eye disease cataract

factors antinuclear

conf = 0.250

15

myasthenia gravis

acetylcholine receptor

coh = 1.000

2

  1. Best δ-maximum scored bridges between the Disease and ProteinGene levels for the the JIA domain, using our reduction method (MDSS). Interestingness measures used are: cohesion (coh), confidence (conf) and f-measure (f1). The column S indicates the number of documents supporting each bridge.