Volume 13 Supplement 2

Proceedings from the Great Lakes Bioinformatics Conference 2011


Edited by Robert A Colvin and Jundong Liu

Great Lakes Bioinformatics Conference 2011. Go to conference site.

Athens, OH, USA

2-4 May 2011

  1. Preface


    Robert A Colvin and Jundong Liu

    BMC Bioinformatics 2012 13(Suppl 2):I1

    Published on: 13 March 2012

  2. Proceedings

    Reordering based integrative expression profiling for microarray classification

    Current network-based microarray analysis uses the information of interactions among concerned genes/gene products, but still considers each gene expression individually. We propose an organized knowledge-supe...

    Xiaogang Wu, Hui Huang, Madhankumar Sonachalam, Sina Reinhard, Jeffrey Shen, Ragini Pandey and Jake Y Chen

    BMC Bioinformatics 2012 13(Suppl 2):S1

    Published on: 13 March 2012

  3. Proceedings

    Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: a study of the HMG domain

    The DNA binding domain of HMG proteins is known to be important in many diseases, with the Sox sub-family of HMG proteins of particular significance. Numerous natural variants in HMG proteins are associated wi...

    Jeremy W Prokop, Thomas C Leeper, Zhong-Hui Duan and Amy Milsted

    BMC Bioinformatics 2012 13(Suppl 2):S3

    Published on: 13 March 2012

  4. Proceedings

    THINK Back: KNowledge-based Interpretation of High Throughput data

    Results of high throughput experiments can be challenging to interpret. Current approaches have relied on bulk processing the set of expression levels, in conjunction with easily obtained external evidence, su...

    Fernando Farfán, Jun Ma, Maureen A Sartor, George Michailidis and Hosagrahar V Jagadish

    BMC Bioinformatics 2012 13(Suppl 2):S4

    Published on: 13 March 2012

  5. Proceedings

    Convergence of genetic influences in comorbidity

    Predisposition to complex diseases is explained in part by genetic variation, and complex diseases are frequently comorbid, consistent with pleiotropic genetic variation influencing comorbidity. Genome Wide As...

    Richard C McEachin, Keerthi S Sannareddy, James D Cavalcoli, Alla Karnovsky, Jacqueline M Vink and Maureen A Sartor

    BMC Bioinformatics 2012 13(Suppl 2):S8

    Published on: 13 March 2012

  6. Proceedings

    Interpolative multidimensional scaling techniques for the identification of clusters in very large sequence sets

    Modern pyrosequencing techniques make it possible to study complex bacterial populations, such as 16S rRNA, directly from environmental or clinical samples without the need for laboratory purification. Alignment ...

    Adam Hughes, Yang Ruan, Saliya Ekanayake, Seung-Hee Bae, Qunfeng Dong, Mina Rho, Judy Qiu and Geoffrey Fox

    BMC Bioinformatics 2012 13(Suppl 2):S9

    Published on: 13 March 2012

  7. Proceedings

    Fold change and p-value cutoffs significantly alter microarray interpretations

    As context is important to gene expression, so is the preprocessing of microarray to transcriptomics. Microarray data suffers from several normalization and significance problems. Arbitrary fold change (FC) cu...

    Mark R Dalman, Anthony Deeter, Gayathri Nimishakavi and Zhong-Hui Duan

    BMC Bioinformatics 2012 13(Suppl 2):S11

    Published on: 13 March 2012