Volume 9 Supplement 6

Symposium of Computations in Bioinformatics and Bioscience (SCBB07)

Research

Edited by Guoqing Lu, Jun Ni, Thomas L Casavant and Brian Athey

Symposium of Computations in Bioinformatics and Bioscience (SCBB07). Go to conference site.

Iowa City, Iowa, USA

13-15 August 2007

  1. Research

    Evolutionary conservation of DNA-contact residues in DNA-binding domains

    DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DNA-binding proteins. In this study, we prop...

    Yao-Lin Chang, Huai-Kuang Tsai, Cheng-Yan Kao, Yung-Chian Chen, Yuh-Jyh Hu and Jinn-Moon Yang

    BMC Bioinformatics 2008 9(Suppl 6):S3

    Published on: 28 May 2008

  2. Research

    Dimension reduction with redundant gene elimination for tumor classification

    Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DNA microarray experiments by commonly used ...

    Xue-Qiang Zeng, Guo-Zheng Li, Jack Y Yang, Mary Qu Yang and Geng-Feng Wu

    BMC Bioinformatics 2008 9(Suppl 6):S8

    Published on: 28 May 2008

  3. Research

    Comparative analyses of bidirectional promoters in vertebrates

    Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes co-regulated by bidirectional promoters t...

    Mary Qu Yang, James Taylor and Laura Elnitski

    BMC Bioinformatics 2008 9(Suppl 6):S9

    Published on: 28 May 2008

  4. Research

    Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical simulation

    In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction of drug interaction on the pathway level is b...

    Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kentaro Watanabe, Kazumi Matsumura and Akihiko Konagaya

    BMC Bioinformatics 2008 9(Suppl 6):S11

    Published on: 28 May 2008

  5. Research

    Quality assessment of peptide tandem mass spectra

    Tandem mass spectrometry has emerged as a cornerstone of high throughput proteomic studies owing in part to various high throughput search engines which are used to interpret these tandem mass spectra. However...

    Fang-Xiang Wu, Pierre Gagné, Arnaud Droit and Guy G Poirier

    BMC Bioinformatics 2008 9(Suppl 6):S13

    Published on: 28 May 2008

  6. Research

    An improved string composition method for sequence comparison

    Historically, two categories of computational algorithms (alignment-based and alignment-free) have been applied to sequence comparison–one of the most fundamental issues in bioinformatics. Multiple sequence al...

    Guoqing Lu, Shunpu Zhang and Xiang Fang

    BMC Bioinformatics 2008 9(Suppl 6):S15

    Published on: 28 May 2008

  7. Research

    A practical comparison of two K-Means clustering algorithms

    Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementations of clustering algorithms yield the sa...

    Gregory A Wilkin and Xiuzhen Huang

    BMC Bioinformatics 2008 9(Suppl 6):S19

    Published on: 28 May 2008