Table 2 Estimated type I error rates for GLOSSI in the simulated examples
From: GLOSSI: a method to assess the association of genetic loci-sets with complex diseases
| Total sample size | Nominal rate, α | Proportion of p-value <α |
|---|---|---|
| 400 | 0.05 | 0.057 |
| 0.01 | 0.011 | |
| 0.001 | 0 | |
| 1200 | 0.05 | 0.045 |
| 0.01 | 0.012 | |
| 0.001 | 0.002 | |
| 2000 | 0.05 | 0.049 |
| 0.01 | 0.010 | |
| 0.001 | 0.003 |