Table 4 Top 10 pathway pairs showing significant difference of Z-transformed interaction scores in the DMD data.
From: Identifying set-wise differential co-expression in gene expression microarray data
Pathway Pair | # of OGs | IS | dZIS | |
|---|---|---|---|---|
| Â | Â | NM | DMD | Â |
Hs_beta-arrestins in GPCR Desensitization (15) D4-GDI Signaling Pathway (22) | 0 | 0.95 | -0.71 | 14.7 |
D4-GDI Signaling Pathway (22) Role of arrestins in the activation and targeting of MAP kinases (22) | 0 | 0.94 | -0.65 | 13.2 |
Eicosanoid Metabolism (25) Lysine_degradation (28) | 0 | 0.94 | -0.66 | 13.2 |
Regulation of hematopoiesis by cytokines (28) Monoamine_GPCRs (34) | 0 | 0.92 | -0.66 | 12.6 |
Aspirin Blocks Signaling Pathway Involved in Platelet Activation (35) D4-GDI Signaling Pathway (22) | 0 | 0.90 | -0.68 | 12.3 |
D4-GDI Signaling Pathway (22) RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage (23) | 0 | 0.79 | -0.80 | 11.5 |
T Helper Cell Surface Molecules (16) TGF beta signaling pathway (34) | 0 | 0.88 | -0.64 | 11.4 |
D4-GDI Signaling Pathway (22) Trka Receptor Signaling Pathway (22) | 0 | 0.84 | -0.68 | 11.0 |
Aspirin Blocks Signaling Pathway Involved in Platelet Activation (35) Msp/Ron Receptor Signaling Pathway (14) | 0 | 0.81 | -0.72 | 10.8 |
Msp/Ron Receptor Signaling Pathway (14) Roles of arrestin-dependent Recruitment of Src Kinases in GPCR Signaling (28) | 0 | 0.79 | -0.72 | 10.5 |