Skip to main content

Table 6 Validation experiment

From: Estimation of tumor heterogeneity using CGH array data

  

Estimated based on (X = S1, S2)

 

Experiment

X

X with 15%

X with 30%

S1

76,24

-

79,21

77,23

S1 with 15%

82,18

80,20

-

81,19

S1 with 30%

84,16

83,17

85,15

-

S1

60,29,11

-

72,20,8

70,21,9

S1 with 15%

76,17,7

66,25,9

-

75,18,7

S1 with 30%

79,15,6

72,20,8

80,14,6

-

S2

62,24,14

-

49,33,18

50,31,19

S2 with 15%

57,28,15

68,20,12

-

57,27,16

S2 with 30%

65,22,13

73,17,10

65,23,12

-

  1. In the "Experiment" column, the estimated subpopulation percentages from the 6 experiments are shown: Two pure tumor samples (S1 and S2), and four samples with tumor mixed with 15 or 30% normal cells. The best fit for S1 is three subpopulations, whereas it is two for "S1 with 15%" and "S1 with 30%"; therefore we show results for both two and three subpopulations to facilitate comparison. The remaining three columns contain percentages estimated from the Experiment column; e.g. to estimate the percentages of the sample with 85% malignant cells and 15% normal cells ("S2 with 15%") from the sample S2 do (0.62·85 + 15, 0.24·85, 0.14·85) = (68, 20, 12).
Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us