BMC Bioinformatics

Table 3 Comparison results of BGMM, BMM and GMM in applications to real data

From: A joint finite mixture model for clustering genes from independent Gaussian and beta distributed data

			All		F		C		P
Dataset	Model	Criterion	Mean	Median	Mean	Median	Mean	Median	Mean	Median
	BMM	4	0.2094	0.2246	0.3410	0.3453	0.3512	0.3552	0.3417	0.3404
Set_{rand 1}	GMM	4	0.1958	0.1658	0.26719	0.3091	0.2925	0.3408	0.2747	0.3398
	BGMM	4	0.1568	0.1047	0.2347	0.1826	0.2663	0.2536	0.2451	0.2287
		BIC/AIC3	0.2071	0.1863	0.3261	0.3490	0.3408	0.3505	0.3331	0.3585
	BMM	ICL	0.2013	0.2013	0.3080	0.3080	0.3631	0.3631	0.3594	0.3594
Set_{rand 2}		AIC	0.1634	0.1505	0.2699	0.2499	0.2890	0.2772	0.2727	0.2427
	GMM	4	0.1958	0.1658	0.2672	0.3091	0.2925	0.3408	0.2747	0.3398
	BGMM	4	0.1436	0.0954	0.2198	0.2199	0.2453	0.2526	0.2311	0.2409
	BMM	4	0.2204	0.2204	0.3748	0.3748	0.3799	0.3799	0.3769	0.3769
Set_{rand 3}	GMM	4	0.1958	0.1658	0.2672	0.3091	0.2925	0.3408	0.2747	0.3398
	BGMM	4	0.1466	0.1155	0.2623	0.2551	0.2838	0.3036	0.2714	0.2811
	BMM	4	0.2407	0.2414	0.3228	0.3055	0.3575	0.3695	0.3300	0.3442
Set_real	GMM	BIC/ICL	0.1973	0.1957	0.2799	0.2999	0.3040	0.3486	0.2883	0.3214
		AIC/AIC3	0.1882	0.1708	0.2747	0.2917	0.3010	0.3325	0.2813	0.3103
	BGMM	4	0.0987	0.0610	0.2455	0.2170	0.2894	0.2999	0.2558	0.2658

Statistics shown in this table are the group average of the p-values of gene enrichment score (each p-value is the average of the p-values of all the ontology groups corresponding to the best clustering result selected by its corresponding model selection criterion). TFs of 'Set_{rand 1}' to 'Set_{rand 3'}were randomly chosen according to certain thresholds (details shown in the text), while TFs of 'Set_real' were carefully selected by BMM.
Note: 'F', 'C' and 'P' stand for the three aspects of gene ontology; 'All' means all aspects are included. '4' represents that all the four criteria indicate the same clustering result. Statistics shown here are all rounded to 4 decimals.

Back to article page

ISSN: 1471-2105

Contact us

General enquiries: journalsubmissions@springernature.com