Average improvements of structure-based sequence alignments. The average accuracies of sequence alignment were computed for each method before and after refinement by the RSE procedure. The corresponding method name is given under each pair of bars along the x-axis, where the bars for <FCAR(0)> and <FCAR(8)> are marked with 0 and 8, respectively. The black portion together with the red tip, when present, represent <FCAR(0)> or <FCAR(8)> before the refinement. The green and red tips indicate the increment and the decrement, respectively, after the refinement.