Skip to main content

Table 3 Models produced by Stepwise Binary Logistic Regression Iteration and M2 Cross-Validation.

From: An iterative strategy combining biophysical criteria and duration hidden Markov models for structural predictions of Chlamydia trachomatis σ66 promoters

SBLR Model

M0

M1

M2

M3

M2 Cross-Validation

Training Set

Deletion

none

CT665

CT681a

CT681b

CT743

CT665

CT681a

CT681b

CT681a

CT681b

CT665

CT681a

CT681b

Variables in Model a

+HMM_SCORE

+STABLE1_37

-POSITION

+CURVE_L32

-GC_L128

+RIGID_L96

+CURVE

+HMM_SCORE

+STABLE1_37

-GC_L32

-POSITION

+CURVE_L32

-CURVE_L64

-GC_L128

+TWIST

+HMM_SCORE

+STABLE1_37

-POSITION

+CURVE_L32

-STABLE_L32

+SIDD_H24

-CURVE_L128

-SIDD_L128

+RIGID_L96

+HMM_SCORE

+STABLE1_37

-POSITION

+CURVE_L32

-STABLE_L32

-STABLE27_37

+CURVE

 

Sensitivity or Recall

19/29

(0.655)

25/25

(1.0)

26/26

(1.0)

25/27

(0.926)

23/26

(0.885)

Specificity

2426/2428

(0.999)

2083/2083

(1.0)

2226/2226

(1.0)

2322/2323

(1.0)

2215/2226

(0.995)

PPV or

Precision

19/21

(0.905)

25/25

(1.0)

26/26

(1.0)

25/26

(0.962)

23/34

(0.676)

NPV

2426/2436

(.996)

2083/2083

(1.0)

2226/2226

(1.0)

2322/2324

(0.999)

2215/2218

(0.999)

Accuracy

2445/2457

(0.995)

2108/2108

(1.0)

2252/2252

(1.0)

2347/2350

(0.999)

2238/2252

(0.994)

AUC b

0.995

1.0

1.0

0.999

0.992

  1. aThe variables are listed in order of entrance into the model and the sign indicates the sign of the coefficient.
  2. bROC analysis Area Under the Curve