Figure 4
From: Using least median of squares for structural superposition of flexible proteins
Superposition comparison for the Topo II structures: 1bgw (gray) and 1bjt (red). (a) The RMSD superposition. (b) The sieve-fit superposition. (c) The global wRMSD superposition (c = 18Å). (d) The LMS superposition, where the maximal residual rmax of 2Å is used in our method. For large displacements, both RMSD and sieve-fit can not catch the similarity of two conformational structures. In contrast, the LMS fit can catch the similarity, where the LMS result is similar to one using wRMSD with the default scaling factor. Arrows denote the improved regions with the LMS fit.