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Table 10 Haplotype relative risk evaluated from genotype distribution of SNPs in GYS2.

From: Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses

  

Frequency

  

SNP

Allele and Haplotype

Case

Control

Relative Risk

95% CI

SNP9

0

0.8057

0.8098

0.9949

(0.9757-1.0146)

 

1

0.1943

0.1902

1.0216

(0.9412-1.1087)

SNP10

0

0.7789

0.8026

0.9705

(0.9505-0.9908)

 

1

0.2211

0.1974

1.1201

(1.0367-1.2102)

SNP11

0

0.7811

0.7818

0.9992

(0.9782-1.0205)

 

1

0.2189

0.2182

1.0030

(0.9299-1.0818)

(SNP9, SNP10)

00

0.7740

0.7967

0.9715

(0.9512-0.9922)

 

01

0.0317

0.0131

2.4258

(1.8357-3.2056)

 

10

0.0049

0.0059

0.8330

(0.4807-1.4433)

 

11

0.1894

0.1843

1.0276

(0.9455-1.1169)

(SNP10, SNP11)

00

0.7494

0.7692

0.9742

(0.9524-0.9965)

 

01

0.0295

0.0334

0.8843

(0.7069-1.1061)

 

10

0.0318

0.0126

2.5275

(1.9064-3.3511)

 

11

0.1894

0.1848

1.0244

(0.9426-1.1134)

  1. The explanation for how the relative risks are obtained and displayed is the same as that given in Table 4. The allelic information for each SNP is given in Table 9. SNP9 = rs6487236, SNP10 = rs1871142 and SNP11 = rs10770836.
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BMC Bioinformatics

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