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Table 3 Prediction results for the training set with 6 combined terms

From: Prediction of antigenic epitopes on protein surfaces by consensus scoring

Complex Unbound No. of Surface Residues No. of Interface Residues Sensitivity a Precision a Specificity a AUC
1AHW_AB:C 1TFH_A 173 25 0.360 0.153 0.662 0.481
1BVK_DE:F 3LZT_ 98 17 0.765 0.361 0.716 0.835
1DQJ_AB:C 3LZT_ 98 20 0.300 0.182 0.654 0.534
1E6J_HL:P 1A43_ 63 13 0.462 0.353 0.780 0.585
1JPS_HL:T 1TFH_B 155 25 0.360 0.170 0.662 0.517
1 MLC_AB:E 3LZT_ 98 16 0.562 0.250 0.671 0.636
1VFB_AB:C 8LYZ_ 107 18 0.833 0.385 0.730 0.833
1WEJ_HL:F 1HRC_ 95 13 0.462 0.188 0.683 0.649
2VIS_AB:C 2VIU_A 247 20 0.900 0.281 0.797 0.901
1BJ1_HLJK:VWb 2VPF_GH 160 35 0.600 0.412 0.760 0.705
1FSK_BC:A 1BV1_ 145 19 0.526 0.233 0.738 0.587
1I9R_HL:ABCb 1ALY_ABC 320 65 0.508 0.292 0.686 0.687
1IQD_AB:C 1D7P_M 127 17 0.765 0.361 0.791 0.848
1K4C_AB:C 1JVM_A 88 16 0.500 0.258 0.681 0.647
1KXQ_H:A 1PPI_ 341 30 0.600 0.148 0.666 0.637
1NCA_HL:N 7NN9_ 263 27 0.556 0.163 0.674 0.684
1NSN_HL:S 1KDC_ 106 23 0.174 0.114 0.627 0.454
1QFW_HL:AB 1HRP_AB 170 17 0.235 0.071 0.660 0.484
1QFW_IM:AB 1HRP_AB 170 17 0.706 0.214 0.712 0.738
2JEL_HL:P 1POH_ 68 18 0.167 0.158 0.680 0.498
1BGX_HL:T 1CMW_A 646 66 0.394 0.124 0.683 0.521
2HMI_CD:AB 1S6P_AB 810 14 0.429 0.024 0.697 0.518
Mean   207 24.1 50.7 0.222 0.7 0.635
  1. a Sensitivity, precision, and specificity were recorded when 55% of surface residues were predicted as interface residues by the single term. We chose the parameter (55%) so that the sensitivity was about 50% in the consensus prediction. bMultiple binding sites.