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Table 2 For each time period listed, an overrepresentation analysis was performed for each gene's coexpression or change in coexpression.

From: A methodology for the analysis of differential coexpression across the human lifespan

The top 5 Gene Ontology (GO) groups for each age range.
Coexpression Lifelong change Early change Late change
translational elongation
hormone activity
ATP metabolic process
Mitochondrial membrane part
aerobic respiration
muscle system process
ribonucleoside triphosphate metabolic process
ribosomal subunit
cellular respiration
nucleotide biosynthetic process
regulation of ubiquitin-protein ligase activity
glucose metabolic process
secretory granule
monovalent inorganic cation transmembrane transporter activity
proteasome complex
pigment granule
calcium ion homeostasis
purine ribonucleotide biosynthetic process
  1. Corrected p values <0.001 were assembled and the top 5 GO groups across all genes are shown for each category.