Table 2 For each time period listed, an overrepresentation analysis was performed for each gene's coexpression or change in coexpression.
From: A methodology for the analysis of differential coexpression across the human lifespan
The top 5 Gene Ontology (GO) groups for each age range. | |||
|---|---|---|---|
Coexpression | Lifelong change | Early change | Late change |
translational elongation (GO:0006414) | Glycolysis (GO:0006096) | hormone activity (GO:0005179) | ATP metabolic process (GO:0046034) |
Mitochondrial membrane part (GO:0044455) | aerobic respiration (GO:0009060) | muscle system process (GO:0003012) | ribonucleoside triphosphate metabolic process (GO:0009199) |
ribosomal subunit (GO:0033279) | cellular respiration (GO:0045333) | Hemostasis (GO:0007599) | nucleotide biosynthetic process (GO:0009165) |
regulation of ubiquitin-protein ligase activity (GO:0051438) | glucose metabolic process (GO:0006006) | secretory granule (GO:0030141) | monovalent inorganic cation transmembrane transporter activity (GO:0015077) |
proteasome complex (GO:0000502) | pigment granule (GO:0048770) | calcium ion homeostasis (GO:0055074) | purine ribonucleotide biosynthetic process (GO:0009152) |