Circular Genome Map. Circular Genome Map view represents the genome in circular form, a visualisation approach typical for circular bacterial chromosomes and plasmids. (A) Map of the Escherichia coli K12 genome. From the outer ring inwards are genes on the direct strand (red), genes on the complementary strand (yellow), tRNAs (green arrows), rRNAs (pink or orange stripes depending on the strand), GC content (brown lines), GC skew (yellow lines). Replication origin and terminus predicted from the cumulative GC skew shift points at single base pair resolution are also labelled, with a yellow line cutting through the genome, segregating the two replichores. This view is useful to see the chromosomal organisation of genes, especially those related to replication. (B) A close up of the region around 500,000 bp. Genes on the direct strand are represented with pink lines and those on the complementary strand are marked in yellow. (C) Close up around the aspartyl-tRNA operon. The strand of tRNA is represented by the direction of the arrowhead. Because tRNAs are very short (typically around 75 bp), their exact positions are also marked with perpendicular stripes.