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Table 1 Evaluation of embedded signal levels with two signal normalizations

From: Generation of Gene Ontology benchmark datasets with various types of positive signal

   

selected percentiles

M.T. meth.

Signal

Classes

 

0

5

25

50

75

95

100

Holm

5

uncorr.

2.54E-05

2.01E-05

1.59E-05

9.99E-06

5.8E-06

4.73E-06

4.26E-06

Holm

10

corrected

0.0556

0.044

0.0348

0.0219

0.0127

0.0104

0.0093

Holm

5

uncorr.

2.54E-05

2E-05

1.58E-05

9.99E-06

5.58E-06

4.73E-06

4.18E-06

Holm

10

corrected

0.0555

0.0437

0.0346

0.0218

0.0122

0.0103

0.0091

FDR

5

uncorr.

0.000124

0.000107

8.69E-05

5.38E-05

4.04E-05

2.75E-05

0.000021

FDR

10

corrected

0.054

0.0481

0.044

0.0281

0.0191

0.0114

0.0093

FDR

5

uncorr.

0.000246

0.000219

0.0002

0.000128

8.69E-05

0.000052

4.23E-05

FDR

10

corrected

0.0547

0.0468

0.0382

0.0236

0.0177

0.0121

0.0092

  1. Table shows the summary of results with reported percentiles. Signal generation is tested with 5 and 10 positive classes and with signal normalizations that use Holm's method and FDR. Note that 5 percentile limit and 95 percentile limit stay within the required 0.01-0.05 range. Minimum and maximum show deviation from the signal range but the deviation is always only appr. 10% of the allowed signal.