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Table 3 Significantly enriched pathway terms in AGCN modules (I = 1.8).

From: Arabidopsis gene co-expression network and its functional modules

module

# pathway genes1

Pathway term2

GO term3

genes in pathway term4

p value

1

192

photosynthesis, light reaction

Photosynthesis

27/27

4.69E-15

3

22

de novo biosynthesis of purine nucleotides

purine nucleoside monophosphate biosynthesis

7/10

2.84E-09

4

5

de novo biosynthesis of pyrimidine deoxyribonucleotides

DNA metabolism

3/6

5.02E-06

11

11

homogalacturonan degradation

cell wall modification

10/34

6.47E-13

45

6

acetyl-CoA biosynthesis (from citrate)

acetyl-CoA biosynthesis

2/2

7.82E-05

67

6

starch degradation

starch metabolism

5/11

3.66E-09

79

8

glucosinolate biosynthesis from tryptophan

indoleacetic acid metabolism

5/5

7.45E-11

80

6

flavonoid biosynthesis

phenylpropanoid metabolism

4/6

3.67E-08

140

3

tryptophan biosynthesis

nitrogen compound metabolism

3/5

2.53E-07

273

3

salicylic acid biosynthesis

aromatic compound biosynthesis

2/3

4.69E-05

  1. 1. The number of genes which were annotated as pathways genes in a module.
  2. 2. Only the most over-represented pathway term was listed for each module.
  3. 3. The column lists the over-represented GO term that matches or relates to the pathway term for each module.
  4. 4. The two values listed in this column refer to the number of genes annotated to the over-represented pathway in the module and the number of genes annotated to the same pathway in the network.