Table 5 Analysis of hot spot predictions for each amino acid type
Mutated amino acid | N mut | TP | TN | FP | FN | P | R | F1 | A |
|---|---|---|---|---|---|---|---|---|---|
Arg | 33 | 5 | 16 | 10 | 2 | 0.33 | 0.71 | 0.45 | 0.64 |
Asn | 22 | 3 | 15 | 1 | 3 | 0.75 | 0.50 | 0.60 | 0.82 |
Asp | 29 | 7 | 15 | 5 | 2 | 0.58 | 0.78 | 0.67 | 0.76 |
Cys | 1 | 0 | 1 | 0 | 0 | NA | NA | NA | 1.00 |
Gln | 21 | 1 | 17 | 2 | 1 | 0.33 | 0.50 | 0.40 | 0.86 |
Glu | 31 | 1 | 22 | 4 | 4 | 0.20 | 0.20 | 0.20 | 0.74 |
His | 13 | 1 | 11 | 1 | 0 | 0.50 | 1.00 | 0.67 | 0.92 |
Ile | 15 | 0 | 11 | 0 | 4 | NA | 0.00 | NA | 0.73 |
Leu | 10 | 0 | 9 | 0 | 1 | NA | 0.00 | 0.00 | 0.90 |
Lys | 32 | 10 | 20 | 1 | 1 | 0.91 | 0.91 | 0.91 | 0.94 |
Met | 2 | 0 | 1 | 1 | 0 | 0.00 | NA | NA | 0.50 |
Phe | 11 | 1 | 8 | 1 | 1 | 0.50 | 0.50 | 0.50 | 0.82 |
Ser | 28 | 1 | 22 | 5 | 0 | 0.17 | 1.00 | 0.29 | 0.82 |
Thr | 24 | 0 | 21 | 2 | 1 | 0.00 | 0.00 | 0.00 | 0.88 |
Trp | 23 | 5 | 13 | 1 | 4 | 0.83 | 0.56 | 0.67 | 0.78 |
Tyr | 44 | 17 | 17 | 7 | 3 | 0.71 | 0.85 | 0.77 | 0.77 |
Val | 10 | 1 | 7 | 1 | 1 | 0.50 | 0.50 | 0.50 | 0.80 |
All | 349 | 53 | 226 | 42 | 28 | 0.56 | 0.65 | 0.60 | 0.80 |
- N
mut
: number of mutations, TP: true positives, TN: true negatives, FP: false positives, FN = false negatives; P: precision, R: recall, F1: F1 score, A: accuracy =
.
.