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Table 5 Degree and clustering coefficient values calculated for the p53 and NF-κB networks

From: Elucidation of functional consequences of signalling pathway interactions

Network p53 Network NF-κB
Uniprot accession Uniprot entry name Degree Clustering coefficient Uniprot accession Uniprot entry name Degree Clustering coefficient
P04637 P53_HUMAN 300 9.10E-04 Q14164 IKKE_HUMAN 324 1.90E-04
Q00987 MDM2_HUMAN 72 0.0133 Q04206 TF65_HUMAN 186 0.01796
P38936 CDN1A_HUMAN 72 0.00509 Q9Y6K9 NEMO_HUMAN 157 0.01764
Q8N726 CD2A2_HUMAN 43 0.00664 Q00653 NFKB2_HUMAN 145 0.03218
P53999 TCP4_HUMAN 12 0 P19838 NFKB1_HUMAN 118 0.04578
Q9Y3B4 PM14_HUMAN 10 0 P25963 IKBA_HUMAN 85 0.05546
P49459 UBE2A_HUMAN 3 0.66667 O14920 IKKB_HUMAN 75 0.07279
Q16665 HIF1A_HUMAN 3 0.66667 Q15653 IKBB_HUMAN 73 0.06963
P06748 NPM_HUMAN 3 0.66667 O15111 IKKA_HUMAN 71 0.08089
P25490 TYY1_HUMAN 3 0.66667 Q01201 RELB_HUMAN 64 0.06399
P62988 UBIQ_HUMAN 3 0.66667 O00221 IKBE_HUMAN 48 0.11702
P51959 CCNG1_HUMAN 3 0.66667 Q04864 REL_HUMAN 38 0.14794
Q92793 CBP_HUMAN 3 0.66667 Q96HD1 CREL1_HUMAN 12 0.68182
P62081 RS7_HUMAN 3 0.66667 P07437 TBB5_HUMAN 12 0.68182
Q99816 TS101_HUMAN 3 0.66667 P62158 CALM_HUMAN 12 0.68182
  1. The table is arranged in descending order. Only the first fifteen proteins within the network with high degree values are listed.