Skip to main content

Table 7 Vertex betweenness values calculated for p53, NF-κB and cell cycle networks

From: Elucidation of functional consequences of signalling pathway interactions

Network p53 Network NF-κB Cell Cycle
Uniprot accession Uniprot entry name B i Uniprot accession Uniprot entry name B i Uniprot accession Uniprot entry name B i
P04637 P53_HUMAN 81612.87 Q14164 IKKE_HUMAN 166771.25 P06400 RB_HUMAN 26218.55
P38936 CDN1A_HUMAN 22279.58 Q04206 TF65_HUMAN 70319.46 P24385 CCND1_HUMAN 9196.14
Q00987 MDM2_HUMAN 18352.39 Q9Y6K9 NEMO_HUMAN 60543.29 Q01094 E2F1_HUMAN 8081.61
Q8N726 CD2A2_HUMAN 9223 Q00653 NFKB2_HUMAN 48010.40 P46527 CDN1B_HUMAN 7318.69
P53999 TCP4_HUMAN 6801.47 P19838 NFKB1_HUMAN 40763.53 P24941 CDK2_HUMAN 1481.39
Q96BK5 PINX1_HUMAN 4250 P25963 IKBA_HUMAN 40680.12 P11802 CDK4_HUMAN 1481.39
Q9Y3B4 PM14_HUMAN 3870 Q15653 IKBB_HUMAN 21318.82 Q13309 SKP2_HUMAN 1195.79
P68400 CSK21_HUMAN 1706.11 Q01201 RELB_HUMAN 17557.99 P78396 CCNA1_HUMAN 1195.79
P20226 TBP_HUMAN 1607.64 O14920 IKKB_HUMAN 15356.68 P38398 BRCA1_HUMAN 872.01
Q09472 EP300_HUMAN 1607.64 O15111 IKKA_HUMAN 14387.00 P08047 SP1_HUMAN 872.01
P41235 HNF4A_HUMAN 1192.02 O00221 IKBE_HUMAN 12109.01 Q9Y3I1 FBX7_HUMAN 614.12
P12004 PCNA_HUMAN 514.08 Q92993 KAT5_HUMAN 8503 Q00526 CDK3_HUMAN 614.12
P21675 TAF1_HUMAN 415.62 Q96HD1 CREL1_HUMAN 7785 P20248 CCNA2_HUMAN 614.12
P06748 NPM_HUMAN 363.33 Q04864 REL_HUMAN 6563.01 P30281 CCND3_HUMAN 614.12
P08238 HS90B_HUMAN 363.33 P07437 TBB5_HUMAN 3982.81 P30279 CCND2_HUMAN 614.12
  1. Results obtained by vertex betweenness produced similar results to the degree of connectivity index reported in Tables 5 and 6.