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Table 1 The property groups used to aggregate similar amino acids.

From: Modular prediction of protein structural classes from sequences of twilight-zone identity with predicting sequences

R groups

Electronic groups

Non-polar aliphatic

A, I, L, V

Donors

A, D, E, P

Glycine

G

Weak donors

I, L, V

Non-polar

F, M, P, W

Acceptors

K, N, R

Polar uncharged

C, N, Q, S, T, Y

Weak acceptors

F, M, Q, T, Y

Polar charged

D, E, H, K, R

Neutral

C, G, H, S, W

Hydrophobicity groups

Exchange groups

Hydrophobic

A, C, F, I, L, M, P, V, W, Y

Group 1

H, R, K,

  

Group 2

D, E, N, Q,

  

Group 3

C

Hydrophilic

D, E, G, H, K, N, Q, R, S, T

Group 4

S, T, P, A, G

  

Group 5

M, I, L, V,

  

Group 6

F, Y, W