Figure 7
From: A white-box approach to microarray probe response characterization: the BaFL pipeline
T-test Power Analysis. The power (sorted on the y axis) for the three probe cleansing methodologies based on t-tests of 4200 ProbeSet values per array (on the x-axis), using the same set of arrays in all cases. Panel A shows the power achieved by the Bhattacharjee adenocarcinoma sample stratification (plotted for RMA, dCHIP, and BaFl), panel B graphs the same analysis results achieved for the normal samples. Panel C presents the calculated sample size required (on the y-axis) in order to achieve a power = 0.8 (at α = 0.05) presuming the ProbeSet variation is adequately reflecting the true variation from the Stearman measurements. Although all 4200 ProbeSets were used in the simulation, the x-axis is truncated to show the beginning of the rise coming off the baseline.