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Table 2 Contributions of genomic data sources

From: Integrative approaches to the prediction of protein functions based on the feature selection

Data source Exhaustive search KL1LR
   # of GO terms (# in union) AUC # of GO terms (# in union) AUC NCG
Protein-protein interactions OPHID 192   0.82 201   0.89 83
Protein domain Interpro 522 (697) 0.87 408 (518) 0.89 266
  Pfam 600   0.86 311   0.89 210
Phenotype MGI 213   0.87 346   0.90 129
Phylogenetic profile BioMart 33 (95) 0.83 59 (166) 0.88 4
  Inparanoid 70   0.84 124   0.88 22
Disease OMIM 41   0.85 32   0.88 3
Gene expression Zhang et al. 28   0.81 147   0.90 10
  Su et al. 21 (55) 0.82 158 (309) 0.89 8
  Sage et al. 16   0.83 113   0.90 7
  1. The numbers of GO terms satisfying the cut-off of prediction accuracies by the AUC and P20R values are presented for each data source along with the average AUC values of the GO terms. For the protein domain, phylogenetic profile, and gene expression data, the number of terms in the union set is shown in parentheses. The numbers of common terms between the two approaches are shown in the last column (NCG).