Table 1 Overview over statistical algorithms for the analysis of gene set enrichment.

overrepresentation analysis

Draghici et al. [1], Hosack et al. [2], Zhang et al. [3], Kathri and Draghici [4], Vêncio and Shmulevich [6]

gene set enrichment analysis

Mootha et al. [7], Subramanian et al. [8], Barry et al. [9], Zahn et al. [10], Efron and Tibshirani [11], Keller et al. [12]

average of single gene statistics

Pavlidis et al. [13], Tian et al. [14], Smyth [15], Jiang and Gentleman [16], Gentleman [17]

parametric methods

Kim and Volsky [18], Dinu et al. [19]

random-set methods

Newton et al. [20]

FDR-based method

Efron [21]

globaltest

Goeman et al. [22]

GlobalAncova

Mansmann und Meister [23], Hummel et al. [24]

Hotelling's T ² -test

Kong et al. [25], Dinu et al. [19]

further procedures

Rahnenführer et al. [26], Edelman et al. [27], Lewin et al. [28], Nacu et al. [29], Adewale et al. [30], Läuter et al. [31]

reviews

Goeman and Bühlmann [5], Liu et al. [32], Chen et al. [33], Nam and Kim [34], Song and Black [35], Dopazo [36]