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Table 1 Overview over statistical algorithms for the analysis of gene set enrichment.

From: A general modular framework for gene set enrichment analysis

Method References
overrepresentation analysis Draghici et al. [1], Hosack et al. [2], Zhang et al. [3], Kathri and Draghici [4], Vêncio and Shmulevich [6]
gene set enrichment analysis Mootha et al. [7], Subramanian et al. [8], Barry et al. [9], Zahn et al. [10], Efron and Tibshirani [11], Keller et al. [12]
average of single gene statistics Pavlidis et al. [13], Tian et al. [14], Smyth [15], Jiang and Gentleman [16], Gentleman [17]
parametric methods Kim and Volsky [18], Dinu et al. [19]
random-set methods Newton et al. [20]
FDR-based method Efron [21]
globaltest Goeman et al. [22]
GlobalAncova Mansmann und Meister [23], Hummel et al. [24]
Hotelling's T 2 -test Kong et al. [25], Dinu et al. [19]
further procedures Rahnenführer et al. [26], Edelman et al. [27], Lewin et al. [28], Nacu et al. [29], Adewale et al. [30], Läuter et al. [31]
reviews Goeman and Bühlmann [5], Liu et al. [32], Chen et al. [33], Nam and Kim [34], Song and Black [35], Dopazo [36]