Figure 6

Probability distribution of approximate sample entropy approach for gene sets 1 and 2 applied to an independent group of patients. Plot of R versus average ApSE for SCC (dots, n = 11)(dark), CIN3(dashed, n = 7)(light), and dApSE (ApSE [SCC]-ApSE [CIN3]) (grey), The value of R which results in the maximum change in ApSE is chosen to represent the gene subset 1 (A), and subset 2 (B). Normal probability distribution of approximate sample entropy calculated for Normal (n = 10), CIN 3 (n = 7) and SCC (n = 11) qRT-PCR validation study for subset 1 (C), and subset 2 (D).