Figure 4

Sequence Ontology-based classification of alternative spliced annotations in five annotated genomes. The Sequence Ontology schema classifies alternatively-transcribed and alternatively-spliced genes into seven different classes; this is done by first grouping their transcript-pairs into three classes: (1) pairs of transcripts that share no sequence in common, (2) transcript-pairs with sequence in common, but which share no exon-boundaries precisely in common, and (3) transcript-pairs that share one or more exons in common. This process results in seven classes of gene; N:0:0 genes for example encode only transcripts that do not overlap. Panel A provides a key for each of the seven classes, consisting of an alternatively spliced gene exhibiting a representative pattern of alternative splicing and its associated classification, e.g. CLASS N:0:0 (Top left). Panel B shows the percentage of genes in each genome falling into each class.