Genotyping and inflated type I error rate in genome-wide association case/control studies

BMC Bioinformatics

Table 2 The percentage of influential genes among the top 100 most significant SNPs, as ranked by LogiCALL, a likelihood ratio test, and a standard test.

Simulated data sets are full described in the Methods Section. The shift is the distance between the and μ_AAand $(μ_{A B}^{A} + μ_{A B}^{U}) / 2$ . The Difference is the distance between $μ_{A B}^{A}$ and $μ_{A B}^{U}$ . RR is the genotype relative risk for subjects homogeneous for the minor allele.

ISSN: 1471-2105