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Table 4 Summary of functional annotation coverage of human interactome genes.

From: Disease candidate gene identification and prioritization using protein interaction networks

Interactome genes with 3 annotations (2440)

 

GO + MP + Pathways

2440

Interactome genes with any 2 annotations (2866)

 

GO + Pathways

1630

GO+MP

1232

MP + Pathways

4

Interactome genes with only 1 annotation (2505)

 

GO only

2448

MP only

10

Pathways only

47

Interactome genes with no annotations (223)

223

Total Interactome genes

8034

  1. About 1/3rd (2505/8034) genes of the interactome are sparsely annotated (GO – Gene Ontology; MP – Mammalian Phenotype; and Pathway annotations).